Abietic acid
Cat. No.：YN251726
| 产品名称: | Abietic acid |
| CAS No.: | 514-10-3 |
| Chemical Name: | (1R,4aR,4bR,10aR)-1,2,3,4,4a,4b,5,6,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic acid |
| Synonyms: | 松香酸 |
| 分子量: | 302.45 |
| 分子式: | C₂₀H₃₀O₂ |
| SMILES: | C[C@@]1(C2[C@@](CCC1)(C)[C@@]3([H])CCC(C(C)C)=CC3=CC2)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Abietic acid 是从Pimenta racemosavar. grissea 中提取出来的二萜化合物，具有抗增殖，抗菌和抗肥胖的活性。Abietic acid 抑制脂氧合酶活性，用于过敏性疾病的研究。 |
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Harris, G.C., and Sanderson, T.F.Resin acids; an improved method of isolation of resin acids the isolation of a new abietic-type acid, neoabietic acidJ. Am. Chem. Soc.70(1),334-339(1948)
Ulusu, N.N., Ercil, D., Sakar, M.K., et al.Abietic acid inhibits lipoxygenase activityPhytother. Res.16(1),88-90(2002)
Roh, S.-S., Park, M.-K., and Kim, Y.-U.Abietic acid from Resina Pini of Pinus species as a testosterone 5α-reductase inhibitorJ. Health Sci.56(4),451-455(2010)
González, M.A., Pérez-Guaita, D., Correa-Royero, J., et al.Synthesis and biological evaluation of dehydroabietic acid derivativesEur. J. Med. Chem.45(2),811-816(2010)
Helfenstein, A., Vahermo, M., Nawrot, D.A., et al.Antibacterial profiling of abietane-type diterpenoidsBioorg. Med. Chem.25(1),132-137(2017)
Hwang, K.H., Ahn, J.Y., Kim, S., et al.Abietic acid has an anti-obesity effect in mice fed a high-fat dietJ. Med. Food14(9),1052-1056(2011)
Takahashi, N., Kawada, T., Goto, T., et al.Abietic acid activates peroxisome proliferator-activated receptor-γ (PPARγ) in RAW264.7 macrophages and 3T3-L1 adipocytes to regulate gene expression involved in inflammation and lipid metabolismFEBS Lett.550(1-3),190-194(2003)
