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Usaramine

Cat. No.:YN251730

  • CAS No. :15503-87-4

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Usaramine
      CAS No.: 15503-87-4
      Chemical Name: (3E,5R,6S,14aR,14bR)-3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione
      Synonyms:光萼野百合碱
      分子量:351.39
      分子式:C₁₈H₂₅NO₆
      SMILES:O=C1O[C@@]2([H])[C@@]3([H])C(COC([C@](CO)(O)[C@H](C)C/C1=C\C)=O)=CCN3CC2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Usaramine 是一种吡咯里嗪类生物碱,从Crolatalaria pallida种子中分离得到。Usaramine 通过减少 50% 以上的生物膜形成而不杀死细菌,显示出显著的抗Staphylococcus epidermidis的生物膜活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • da Silva Negreiros Neto, T., Gardner, D., Hallwass, F., et al.Activity of pyrrolizidine alkaloids against biofilm formation and Trichomonas vaginalisBiomed. Pharmacother.83,323-329(2016)

      Culvenor, C.C.J., Edgar, J.A., Jago, M.V., et al.Hepato- and pneumotoxicity of pyrrolizidine alkaloids and derivatives in relation to molecular structureChem. Biol. Interact.12(3-4),299-324(1976)

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