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Difloxacin hydrochloride

Cat. No.:YN251745

  • CAS No. :91296-86-5

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    • 参考文献
    • 产品名称: Difloxacin hydrochloride
      CAS No.: 91296-86-5
      Chemical Name: 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride
      Synonyms:Difloxacin HCl,盐酸二氟沙星
      分子量:435.85
      分子式:C₂₁H₂₀ClF₂N₃O₃
      SMILES:O=C(C1=CN(C2=CC=C(F)C=C2)C3=C(C=C(F)C(N4CCN(C)CC4)=C3)C1=O)O.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Difloxacin hydrochloride 是一种广谱抗菌药物。Difloxacin hydrochloride 通过干扰 DNA 促旋酶和拓扑异构酶 IV 的活性可抑制细菌 DNA 促旋酶和显示出浓度依赖性的杀菌作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Bansal, M.B., and Thadepalli, H.Activity of difloxacin (A-56619) and A-56620 against clinical anaerobic bacteria in vitroAntimicrob. Agents Chemother.31(4),619-621(1987)

      Thadepalli, H., Gollapudi, S.V., and Chuah, S.K.Therapeutic evaluation of difloxacin (A-56619) and A-56620 for experimentally induced Bacteroides fragilis-associated intra-abdominal abscessAntimicrob. Agents Chemother.30(4),574-576(1986)

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