ZM-447439

Cat. No.：331771-20-1

CAS No. ：331771-20-1

产品名称:	ZM-447439
CAS No.:	331771-20-1
Chemical Name:
Synonyms:	ZM 447439
分子量:	513.59
分子式:	C₂₉H₃₁N₅O₄
SMILES:	O=C(NC1=CC=C(NC2=C(C(C=C3OCCCN4CCOCC4)=NC=N2)C=C3OC)C=C1)C5=CC=CC=C5
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Carmena, M., Ruchaud, S., and Earnshaw, W.C.Making the Auroras glow: Regulation of Aurora A and B kinase function by interacting proteinsCurr. Opin. Cell Biol.21(6),796-805(2009)', 'Girdler, F., Gascoigne, K.E., Eyers, P.A., et al.Validating Aurora B as an anti-cancer drug targetJ. Cell Sci.119(Pt 17),3664-3675(2006)', 'Ditchfield, C., Johnson, V.L., Tighe, A., et al.Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochoresJ. Cell Biol.161(2),267-280(2003)', 'Gadea, B.B., and Ruderman, J.V.Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extractsMol. Biol. Cell16(3),1305-1318(2005)