8-Bromo-cGMP sodium
Cat. No.：YN360079
CAS No. ：51116-01-9
| 产品名称: | 8-Bromo-cGMP sodium |
| CAS No.: | 51116-01-9 |
| Chemical Name: | 8-bromo-guanosine cyclic 3',5'-(hydrogen phosphate), monosodium salt |
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| 分子量: | 446.08 |
| 分子式: | C₁₀H₁₀BrN₅NaO₇P |
| SMILES: | O=C1C2=C(N([C@H]3[C@H](O)[C@@](OP(OC4)(O[Na])=O)([H])[C@]4([H])O3)C(Br)=N2)NC(N)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 8-Bromo-cGMP sodium 是 cGMP 的膜渗透性类似物，是一种PKG激活剂，可显着抑制Ca2+宏观电流并损害高 K+刺激的胰岛素释放。8-Bromo-cGMP sodium 具有镇痛作用。 |
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Rashatwar, S.S., Cornwell, T.L., and Lincoln, T.M.Effects of 8-bromo-cGMP on Ca2+ levels in vascular smooth muscle cells: Possible regulation of Ca2+-ATPase by cGMP-dependent protein kinaseProc. Natl. Acad. Sci. USA84(16),5685-5689(1987)
Choi, J., and Farley, J.M.Effects of 8-bromo-cyclic GMP on membrane potential of single swine tracheal smooth muscle cellsJ. Pharmacol. Exp. Ther.285(2),588-594(1998)
