eCF506
Cat. No.：YN440148
CAS No. ：1914078-41-3
规格
价格(RMB)
库存
| 产品名称: | eCF506 |
| CAS No.: | 1914078-41-3 |
| Chemical Name: | N-[4-[4-amino-1-[2-[4-(dimethylamino)-1-piperidinyl]ethyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]-carbamic acid, 1,1-dimethylethyl ester |
| Synonyms: | eCF 506;eCF-506 |
| 分子量: | 510.63 |
| 分子式: | C₂₆H₃₈N₈O₃ |
| SMILES: | NC1=C2C(C3=CC(OC)=C(NC(OC(C)(C)C)=O)C=C3)=NN(CCN4CCC(N(C)C)CC4)C2=NC=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | eCF506是高效，有口服活性的非受体酪氨酸激酶Src的抑制剂，IC50值小于0.5 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Fraser, C., Dawson, J.C., Dowling, R., et al.Rapid discovery and structure-activity relationships of pyrazolopyrimidines that potently suppress breast cancer cell growth via SRC kinase inhibition with exceptional selectivity over ABL kinaseJ. Med. Chem.59(10),4697-4710(2016)
