Atovaquone D4

Cat. No.：2070015-14-2

CAS No. ：2070015-14-2

产品名称:	Atovaquone D4
CAS No.:	2070015-14-2
Chemical Name:
Synonyms:	阿托伐醌D4
分子量:	370.86
分子式:	C₂₂H₁₅D₄ClO₃
SMILES:	O=C1C2=C(C(C(O)=C1[C@@H]3CC[C@@H](C4=CC=C(Cl)C=C4)CC3)=O)C([2H])=C([2H])C([2H])=C2[2H]
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Kessl, J.J., Lange, B.B., Merbitz-Zahradnik, T., et al.Molecular basis for atovaquone binding to the cytochrome bc1 complexJ. Biol. Chem.278(33),31312-31318(2003)', "Fry, M., and Pudney, M.Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3-hydroxy-1,4-naphthoquinone (566C80)Biochem. Pharmacol.43(7),1545-1553(1992)", 'Srivastava, I.K., Rottenberg, H., and Vaidya, A.B.Atovaquone, a broad spectrum antiparasitic drug, collapses mitochondrial membrane potential in a malarial parasiteJ. Biol. Chem.272(7),3961-3966(1997)', 'Rijpma, S.R., van den Heuvel, J.J., van der Velden, M., et al.Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activityMalar. J.13,359(2014)', 'Romand, S., Pudney, M., and Derouin, F.In vitro and in vivo activities of the hydroxynaphthoquinone atovaquone alone or combined with pyrimethamine, sulfadiazine, clarithromycin, or minocycline against Toxoplasma gondiiAntimicrob. Agents Chemother.37(11),2371-2378(1993)