Seocalcitol
Cat. No.：YN470031
CAS No. ：134404-52-7
规格
价格(RMB)
库存
| 产品名称: | Seocalcitol |
| CAS No.: | 134404-52-7 |
| Chemical Name: | (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4E)-6-ethyl-6-hydroxy-1-methyl-2,4-octadien-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol |
| Synonyms: | EB 1089 |
| 分子量: | 454.68 |
| 分子式: | C₃₀H₄₆O₃ |
| SMILES: | O[C@H]1C[C@@H](C(/C(C1)=C\C=C2[C@@]3(CC[C@@H]([C@]3(CCC\2)C)[C@@H](/C=C/C=C/C(CC)(CC)O)C)[H])=C)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Seocalcitol 是一种 vitamin D 类似物，作用于人骨肉瘤 MG-63 细胞，结合vitamin D受体蛋白，Kd为 0.27 nM。 |
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Hansen, C.M., Hamberg, K.J., Binderup, E., et al.Seocalcitol (EB 1089): A vitamin D analogue of anti-cancer potential. Background, design, synthesis, pre-clinical and clinical evaluationCurr. Pharm. Des.6(7),803-828(2000)
James, S.Y., Mercer, E., Brady, M., et al.EB1089, a synthetic analogue of vitamin D, induces apoptosis in breast cancer cells in vivo and in vitroBr. J. Pharmacol.125(5),953-962(1998)
