BAY885
Cat. No.：YN350075
CAS No. ：2307249-33-6
规格
价格(RMB)
库存
| 产品名称: | BAY885 |
| CAS No.: | 2307249-33-6 |
| Chemical Name: | [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-methanone |
| Synonyms: | BAY885 |
| 分子量: | 515.53 |
| 分子式: | C₂₅H₂₈F₃N₇O₂ |
| SMILES: | O=C(C1=CC=C(OC(F)(F)F)C=C1N)N(CC2)CCC2C3=NC=NC4=CC(N5CCN(C)CC5)=CN=C43 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BAY885 是一种高效的选择性ERK5抑制剂，IC50为 35 nM，对其他激酶的抑制作用较弱。 |
| IC50和靶点: | [{name:"ERK5:35 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Nguyen, D., Lemos, C., Wortmann, L., et al.Discovery and characterization of the potent and highly selective (piperidin-4-yl)pyrido[3,2-d]pyrimidine based in vitro probe BAY-885 for the kinase ERK5J. Med. Chem.62(2),928-940(2019)
