Ulixertinib
Cat. No.：YN350170
CAS No. ：869886-67-9
| 产品名称: | Ulixertinib |
| CAS No.: | 869886-67-9 |
| Chemical Name: | |
| Synonyms: | BVD-523; VRT752271 |
| 分子量: | 433.33 |
| 分子式: | C₂₁H₂₂Cl₂N₄O₂ |
| SMILES: | O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ulixertinib (BVD-523; VRT752271) 是一种有效、可口服、高度选择性、ATP-竞争性、可逆、共价的ERK1/2抑制剂，对 ERK2 的IC50值 <0.3 nM。Ulixertinib (BVD-523; VRT752271) 可抑制 ERK2 和 下游蛋白 RSK 的磷酸化。 |
| IC50和靶点: | [{name:"ERK2:0.3 nM (IC50, at KM ATP (60 μM))'}, 'ERK1'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
