PD-334581
Cat. No.：YN350278
| 产品名称: | PD-334581 |
| CAS No.: | 108923-79-1 |
| Chemical Name: | 2,3-bis[amino(methylthio)methylene]-butanedinitrile |
| Synonyms: | |
| 分子量: | 226.32396 |
| 分子式: | C8H10N4S2 |
| SMILES: | N#CC(C(C#N)=C(N)SC)=C(N)SC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | U0124 是一种无活性的 U0126 类似物，对 c-Fos 和 c-Jun 蛋白或 mRNA 水平没有影响。 U0126 是一种MEK抑制剂。 U0124 在浓度高达 100 μM 时也不会抑制MEK。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Favata, M.F., Horiuchi, K.Y., Manos, E.J., et al.Identification of a novel inhibitor of mitogen-activated protein kinase kinaseJ. Biol. Chem.273(29),18623-18632(1998)
Zipperly, M.E., Sultan, F.A., Graham, G.-E., et al.Regulation of dopamine-dependent transcription and cocaine action by Gadd45bNeuropsychopharmacology46(4),709-720(2021)
