Rineterkib
Cat. No.：YN350317
| 产品名称: | Rineterkib |
| CAS No.: | 1715025-32-3 |
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| 分子量: | 578.42 |
| 分子式: | C26H27BrF3N5O2 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rineterkib (compound B) 是具有口服活性的ERK1和ERK2的抑制剂，通过激活 MAPK 通路中的突变来发挥抗增生作用。这种活性与 KRAS-突变型非小细胞肺癌、BRAF-突变型非小细胞肺癌、KRAS-突变型胰腺癌、KRAS -突变型结肠癌以及 KRAS 突变型卵巢癌尤为相关。Rineterkib hydrochloride 也能抑制RAF。 |
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