ICG001
Cat. No.：YN450185
CAS No. ：847591-62-2
| 产品名称: | ICG001 |
| CAS No.: | 847591-62-2 |
| Chemical Name: | (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide; |
| Synonyms: | PRI-724 isomer,PRI-724 |
| 分子量: | 548.63 |
| 分子式: | C33H32N4O4 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ICG001 拮抗 Wnt/β-catenin/TCF 介导的转录，并特异性结合元件结合蛋白 (CREB) 结合蛋白 (CBP)，IC50 为 3 μM，但不是相关的转录共激活因子 p300。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
McMillan, M., et al.: Drug Discov. Today, 10, 1467 (2005), Brantjes, H., et al.: Biol. Chem., 383, 255 (2002), Nusse, R., et al.: Cell Res., 15, 28 (2005), Eguchi, M., et al.: Med. Chem., 1, 467 (2005),
