Gallocyanine chloride
Cat. No.：YN450187
CAS No. ：1562-85-2
| 产品名称: | Gallocyanine chloride |
| CAS No.: | 1562-85-2 |
| Chemical Name: | 1-carboxy-7-(dimethylamino)-3,4-dihydroxy-phenoxazin-5-ium, monochloride |
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| 分子量: | 336.7 |
| 分子式: | C15H13N2O5 • Cl |
| SMILES: | OC(C1=CC(O)=C(O)C2=[O+]C3=CC(N(C)C)=CC=C3N=C21)=O.[Cl-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Gallocyanine chloride 是一种合成的蓝色染料，通过破坏DKK1/LRP6相互作用来阻断DKK1抑制活性。 它与 LRP6 的结合较弱 (抑制 DKK1 结合的 IC50约为 3 μM)。Gallocyanine chloride染料可用于研究阿尔茨海默病和相关神经退行性 tau 蛋白病的潜在活性分子。 |
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Mpousis, S., Thysiadis, S., Avramidis, N., et al.Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathiesEur. J. Med. Chem.108,28-38(2016)
