MBM-55S
Cat. No.：YN350338
| 产品名称: | MBM-55S |
| CAS No.: | 2083624-07-9 |
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| 分子量: | 734.738 |
| 分子式: | C36H39FN6O10 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MBM-55S 是有效的NIMA-related kinase 2 (Nek2)抑制剂，IC50值为 1 nM，是其他激酶选择性的 20 倍甚至更高，除了RSK1(IC50=5.4 nM) 和 DYRK1a (IC50=6.5 nM)。MBM-55S 通过诱导细胞周期停滞和凋亡 (apoptosis) 抑制癌细胞的增殖。具有抗肿瘤活性，且对小鼠没有明显的毒性。 |
| IC50和靶点: | [{name:"RSK1:5.4 nM (IC50)"},{name: "DYRK1A:6.5 nM (IC50)"}] |
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