Etrasimod
Cat. No.：YN320643
CAS No. ：1206123-37-6
规格
价格(RMB)
库存
| 产品名称: | Etrasimod |
| CAS No.: | 1206123-37-6 |
| Chemical Name: | (3R)-7-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-1,2,3,4-tetrahydro-cyclopent[b]indole-3-acetic acid |
| Synonyms: | APD334 |
| 分子量: | 457.48 |
| 分子式: | C₂₆H₂₆F₃NO₃ |
| SMILES: | FC(F)(F)C1=CC(COC2=CC=C(NC3=C4CC[C@@H]3CC(O)=O)C4=C2)=CC=C1C5CCCC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Etrasimod (APD334) 是高效的有选择性和口服活性的S1P1受体拮抗剂，在CHO细胞中的IC50值为1.88 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Buzard, D.J., Kim, S.H., Lopez, L., et al.Discovery of APD334: Design of a clinical stage functional antagonist of the sphingosine-1-phosphate-1 receptorACS Med. Chem. Lett.5(12),1313-1317(2014)
