Propranolol
Cat. No.:YN321539
| 产品名称: | Propranolol |
| CAS No.: | 525-66-6 |
| Chemical Name: | 1[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol |
| Synonyms: | |
| 分子量: | 259.34 |
| 分子式: | C₁₆H₂₁NO₂ |
| SMILES: | OC(COC1=C2C=CC=CC2=CC=C1)CNC(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Propranolol 是一种非选择性的β-adrenergic receptor (βAR)拮抗剂,对 β1AR 和 β2AR 具有高亲和力,Ki值分别为 1.8 nM 和 0.8 nM。Propranolol 抑制[3H]-DHA 与大鼠脑膜制剂的结合,IC50为 12 nM。Propranolol 用于高血压,嗜铬细胞瘤,心肌梗塞,心律不齐,心绞痛和肥大心肌病的相关研究。 |
| IC50和靶点: | |
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Blaes, A. H., et al.: Clin. Cancer Res., 26, 1781 (2020)
Zaccara, G., et al.: Acta Neurol. Scand., 142, 37 (2020)