Benzamil
Cat. No.:YN360876
| 产品名称: | Benzamil |
| CAS No.: | 2898-76-2 |
| Chemical Name: | |
| Synonyms: | Benzylamiloride |
| 分子量: | 319.75 |
| 分子式: | C₁₃H₁₄ClN₇O |
| SMILES: | O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=CC=C2)=N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Benzamil (Benzylamiloride),是 Amiloride 类似物,是一种 Na+/Ca2+交换体(NCX)抑制剂,(IC50~100 nM)。Benzamil 也是一种非选择性Deg/epithelial sodium channels (ENaC)阻滞剂,能增强肌源性血管收缩。Benzamil 抑制 TRPP3 介导的 Ca2+激活电流,IC50为 1.1 μM。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |