Leukotriene B4
Cat. No.:YN370377
CAS No. :71160-24-2
产品名称: | Leukotriene B4 |
CAS No.: | 71160-24-2 |
Chemical Name: | 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid |
Synonyms: | LTB4; 5(S),12(R)-DiHETE |
分子量: | 336.47 |
分子式: | C₂₀H₃₂O₄ |
SMILES: | CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Leukotriene B4 是一种 PROTAC linker,属于 alkyl chain 类。可用于合成 PROTAC 分子。 |
IC50和靶点: | |
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Rådmark, O., Malmsten, C., Samuelsson, B., et al.Leukotriene A: Stereochemistry and enzymatic conversion to leukotriene BBiochem. Biophys. Res. Commun.92(3),954-961(1980)
Ford-Hutchinson, A.W., Bray, M.A., Doig, M.V., et al.Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytesNature286(5770),264-265(1980)
McGee, J., and Fitzpatrick, F.Enzymatic hydration of leukotriene A4. Purification and characterization of a novel epoxide hydrolase from human erythrocytesJ. Biol. Chem.260(23),12832-12837(1985)
Ford-Hutchinson, A.W.Leukotriene B4 in inflammationCrit. Rev. Immunol.10(1),1-12(1990)
McMillan, R.M., and Foster, S.J.Leukotriene B4 and inflammatory diseaseAgents Actions24(1-2),114-119(1988)