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Leukotriene B4

Cat. No.:YN370377

  • CAS No. :71160-24-2

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    • 产品名称: Leukotriene B4
      CAS No.: 71160-24-2
      Chemical Name: 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
      Synonyms:LTB4; 5(S),12(R)-DiHETE
      分子量:336.47
      分子式:C₂₀H₃₂O₄
      SMILES:CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Leukotriene B4 是一种 PROTAC linker,属于 alkyl chain 类。可用于合成 PROTAC 分子。
      IC50和靶点:
      In Vitro:
      In Vivo:
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    • Rådmark, O., Malmsten, C., Samuelsson, B., et al.Leukotriene A: Stereochemistry and enzymatic conversion to leukotriene BBiochem. Biophys. Res. Commun.92(3),954-961(1980)

      Ford-Hutchinson, A.W., Bray, M.A., Doig, M.V., et al.Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytesNature286(5770),264-265(1980)

      McGee, J., and Fitzpatrick, F.Enzymatic hydration of leukotriene A4. Purification and characterization of a novel epoxide hydrolase from human erythrocytesJ. Biol. Chem.260(23),12832-12837(1985)

      Ford-Hutchinson, A.W.Leukotriene B4 in inflammationCrit. Rev. Immunol.10(1),1-12(1990)

      McMillan, R.M., and Foster, S.J.Leukotriene B4 and inflammatory diseaseAgents Actions24(1-2),114-119(1988)

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