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> 产品中心 > 抑制剂 & 激动剂 > Metabolic Enzyme/Protease > Endogenous Metabolite

1-Methyladenosine

Cat. No.:YN370634

  • CAS No. :15763-06-1

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    • 参考文献
    • 产品名称: 1-Methyladenosine
      CAS No.: 15763-06-1
      Chemical Name: 1-methyl-adenosine
      Synonyms:
      分子量:281.27
      分子式:C₁₁H₁₅N₅O₄
      SMILES:OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN(C)C3=N)O1)O)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: 1-Methyladenosine 是一种 RNA 修饰,主要来自两种不同的反应类型,一种是酶催化的,另一种是 RNA 与某些烷化剂反应的结果。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Munns, T.W., and Sims, H.F.Methylation and processing of transfer ribonucleic acid in mammalian and bacterial cellsJ. Biol. Chem.250(6),2143-2149(1975)

      Vold, B.Modified nucleosides of Bacillus subtilis transfer ribonucleic acidsJ. Bacteriol.127(1),258-267(1976)

      Chujo, T., and Suzuki, T.Trmt61B is a methyltransferase responsible for 1-methyladenosine at position 58 of human mitochondrial tRNAsRNA18(12),2269-2276(2012)

      Reynaud, C., Bruno, C., Boullanger, P., et al.Monitoring of urinary excretion of modified nucleosides in cancer patients using a set of six monoclonal antibodiesCancer Lett.,255-262(1991)

      Seidel, A., Brunner, S., Seidel, P., et al.Modified nucleosides: An accurate tumour marker for clinical diagnosis of cancer, early detection and therapy controlBr. J. Cancer.94(11),1726-1733(2006)

      Hsu, W.Y., Chen, C.J., Huang, Y.C., et al.Urinary nucleosides as biomarkers of breast, colon, lung, and gastric cancer in TaiwanesePLoS One8(12),1-8(2013)

      Chen, F., Xue, J., Zhou, L., et al.Identification of serum biomarkers of hepatocarcinoma through liquid chromatography/mass spectrometry-based metabonomic methodAnal. Bioanal. Chem.401(6),1899-1904(2011)

      Tebib, J.G., Reynaud, C., Cedoz, J.P., et al.Relationship between urinary excretion of modified nucleosides and rheumatoid arthritis processBr. J. Rheumatol.36(9),990-995(1997)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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