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3-Nitro-L-tyrosine

Cat. No.:YN370688

  • CAS No. :621-44-3

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 3-Nitro-L-tyrosine
      CAS No.: 621-44-3
      Chemical Name: 3-nitro-L-tyrosine
      Synonyms:3-NT, N-Tyr, MNT
      分子量:226.19
      分子式:C₉H₁₀N₂O₅
      SMILES:N[C@@H](CC1=CC([N+]([O-])=O)=C(C=C1)O)C(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 3-Nitro-L-tyrosine 在系统自免疫原性条件下,可作为无氮自由基修饰蛋白的生物标记物。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Beckman, J.S., and Koppenol, W.H.Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the uglyAm. J. Physiol.271(5 Pt 1),C1424-C1437(1996)

      Beckman, J.S., Ye, Y.Z., Anderson, P.G., et al.Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistryBiol. Chem. Hoppe Seyler375(2),81-88(1994)

      Abe, K., Pan, L.H., Watanabe, M., et al.Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosisNeurol. Res.19(2),124-128(1997)

      Ferrante, R.J., Shinobu, L.A., Schulz, J.B., et al.Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutationAnn. Neurol.42(3),326-334(1997)

      Haddad, I.Y., Pataki, G., Hu, P., et al.Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injuryJ. Clin. Invest.94,2407-2413(1994)

      Ohya, M., Marukawa, S., Inoue, T., et al.Plasma nitrotyrosine concentration relates to prognosis in human septic shockShock18(2),116-118(2002)

      Tsikas, D., Schwedhelm, E., Stutzer, F.K., et al.Accurate quantification of basal plasma levels of 3-nitrotyrosine and 3-nitrotyrosinoalbumin by gas chromatography-tandem mass spectrometryJ. Chromatogr. B Analyt. Technol. Biomed. Life Sci.784(1),77-90(2003)

      Schwedhelm, E., Tsikas, D., Gutzki, F.M., et al.Gas chromatographic-tandem mass spectrometric quantification of free 3-nitrotyrosine in human plasma at the basal stateAnal. Biochem.276,195-203(1999)

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