7α-Hydroxy-4-cholesten-3-one
Cat. No.：YN370691
| 产品名称: | 7α-Hydroxy-4-cholesten-3-one |
| CAS No.: | 3862-25-7 |
| Chemical Name: | 7α-hydroxy-cholest-4-en-3-one |
| Synonyms: | |
| 分子量: | 400.64 |
| 分子式: | C₂₇H₄₄O₂ |
| SMILES: | CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)CC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 7α-Hydroxy-4-cholesten-3-one 是一种由胆固醇合成胆汁酸的中间体。7α-Hydroxy-4-cholesten-3-one 是一种孕烷 X 受体 (PXR) 激动剂。7α-Hydroxy-4-cholesten-3-one 是胆汁酸流失，肠易激综合征和其他与胆汁酸生物合成缺陷有关的疾病的生物标志物。7α-Hydroxy-cholest-4-en-3-one 也是一种 CYP8B1 的生理底物。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Russell, D.W.The enzymes, regulation, and genetics of bile acid synthesisAnnu. Rev. Biochem.72,137-174(2003)
Axelson, M., Aly, A., and Sjövall, J.Levels of 7α-hydroxy-4-cholesten-3-one in plasma reflect rates of bile acid synthesis in manFEBS Lett.239(2),324-328(1988)
