3b-Hydroxy-5-cholenoic acid
Cat. No.：YN370721
CAS No. ：5255-17-4
| 产品名称: | 3b-Hydroxy-5-cholenoic acid |
| CAS No.: | 5255-17-4 |
| Chemical Name: | 3β-hydroxy-chol-5-en-24-oic acid |
| Synonyms: | |
| 分子量: | 374.56 |
| 分子式: | C₂₄H₃₈O₃ |
| SMILES: | C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3b-Hydroxy-5-cholenoic acid 是一种内源性的单羟基胆酸，在患有肝胆管状发育不全的儿童体内大量存在。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Lee, C., Martin, K.O., and Javitt, N.B.Bile acid synthesis: 7α-Hydroxylation of intermediates in the sterol 27-hydroxylase metabolic pathwayJ. Lipid. Res.37(6),1356-1362(2006)
Setchell, K.D.R., Schwarz, M., O'Connell, N.C., et al.Identification of a new inborn error in bile acid synthesis: Mutation of the oxysterol 7α-hydroxylase gene causes severe neonatal liver diseaseJ. Clin. Invest.102(9),1690-1703(1998)
Sugiyama, K., Okuyama, S., Imoto, M., et al.Clinical evaluation of serum 3β-hydroxy-5-cholenoic acid in hepatobiliary diseaseGastroenterologia Japonica21(6),608-616(1986)
