7-Methylguanine
Cat. No.：YN370728
CAS No. ：578-76-7
| 产品名称: | 7-Methylguanine |
| CAS No.: | 578-76-7 |
| Chemical Name: | 2-amino-1,7-dihydro-7-methyl-6H-purin-6-one |
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| 分子量: | 165.15 |
| 分子式: | C₆H₇N₅O |
| SMILES: | O=C1NC(N)=NC2=C1N(C)C=N2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 7-Methylguanine是DNA甲基化的代谢产物。 它可以通过甲基化试剂产生，并用作蛋白质-DNA相互作用的探针和DNA测序方法的关键组分。 |
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Kozma, A., Ibáñez, S., Silaghi-Dumitrescu, R., et al.7-Methylguanine: Protonation, formation of linkage isomers with trans-(NH3)2Pt(II), and base pairing propertiesDalton Trans.41,6094-6103(2012)
Lee, S., Bowman, B.R., Ueno, Y., et al.Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanineJ. Am. Chem. Soc.130(35),11570-11571(2008)
Lee, H.L., Hsueh, Y.M., Chung, C.J., et al.Correlation between the urine profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolites and N7-methylguanine in urothelial carcinoma patientsCancer Epigemiol. Biomarkers Prev.17(12),3390-3395(2008)
