Oxypurinol
Cat. No.:YN372564
产品名称: | Oxypurinol |
CAS No.: | 2465-59-0 |
Chemical Name: | 1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione |
Synonyms: | Oxipurinol |
分子量: | 152.11 |
分子式: | C₅H₄N₄O₂ |
SMILES: | O=C1C2=C(NN=C2)NC(N1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Oxopurinol (Oxipurinol) 是 Allopurinol 的主要活性代谢产物,是一种黄嘌呤氧化酶 (xanthine oxidase) 抑制剂。Oxipurinol 可用于调节血尿酸水平,有潜力用于痛风的研究。 |
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Becker, M.A., Argubright, K.F., Fox, R.M., et al.Oxipurinol-associated inhibition of pyrimidine synthesis in human lymphoblastsMol. Pharmacol.10(4),657-668(1974)
Kaiser, W.J., and Stocker, K.Purine and pyrimidine biosynthesis in Neurospora crassa and human skin fibroblasts. Alteration by ribosides and ribotides of allopurinol and oxipurinolAdv. Exp. Med. Biol.41,629-635(1974)
Marr, J.J., and Berens, R.L.Antileishmanial effect of allopurinol. II. Relationship of adenine metabolism in Leishmania species to the action of allopurinolJ. Infect. Dis.136(6),724-732(1977)