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Oxypurinol

Cat. No.:YN372564

  • CAS No. :2465-59-0

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    • 参考文献
    • 产品名称: Oxypurinol
      CAS No.: 2465-59-0
      Chemical Name: 1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
      Synonyms:Oxipurinol
      分子量:152.11
      分子式:C₅H₄N₄O₂
      SMILES:O=C1C2=C(NN=C2)NC(N1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Oxopurinol (Oxipurinol) 是 Allopurinol 的主要活性代谢产物,是一种黄嘌呤氧化酶 (xanthine oxidase) 抑制剂。Oxipurinol 可用于调节血尿酸水平,有潜力用于痛风的研究。
      IC50和靶点:
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    • Becker, M.A., Argubright, K.F., Fox, R.M., et al.Oxipurinol-associated inhibition of pyrimidine synthesis in human lymphoblastsMol. Pharmacol.10(4),657-668(1974)

      Kaiser, W.J., and Stocker, K.Purine and pyrimidine biosynthesis in Neurospora crassa and human skin fibroblasts. Alteration by ribosides and ribotides of allopurinol and oxipurinolAdv. Exp. Med. Biol.41,629-635(1974)

      Marr, J.J., and Berens, R.L.Antileishmanial effect of allopurinol. II. Relationship of adenine metabolism in Leishmania species to the action of allopurinolJ. Infect. Dis.136(6),724-732(1977)

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