Menadione
Cat. No.:YN372780
产品名称: | Menadione |
CAS No.: | 58-27-5 |
Chemical Name: | 2-methyl-1,4-naphthalenedione |
Synonyms: | 维生素K3; Vitamin K3 |
分子量: | 172.18 |
分子式: | C₁₁H₈O₂ |
SMILES: | O=C1C(C)=CC(C2=C1C=CC=C2)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Menadione是合成的萘醌,可在体内转化为活性维生素K2。 |
IC50和靶点: | |
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Scott, G.K., Atsriku, C., Kaminker, P., et al.Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylationMol. Pharmacol.68(3),606-615(2005)
Pinilla, I., Izaquirre, L.B., Gonzalvo, F., et al.In vitro vitamin K3 effect on conjunctival fibroblast migration and proliferationScientificWorldJournal2014,(2014)
Chun, Y.J., Lee, B.Y., Yang, S.A., et al.Induction of cytochrome P450 1A1 gene expression by a vitamin K3 analog in mouse hepatoma Hepa-1c1c7 cellsMol. Cells12(2),190-196(2001)