Methylcobalamin
Cat. No.：YN372822
CAS No. ：13422-55-4
| 产品名称: | Methylcobalamin |
| CAS No.: | 13422-55-4 |
| Chemical Name: | co-methyl-cobinamide, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3) |
| Synonyms: | 甲钴胺; CH3-B12 |
| 分子量: | 1344.38 |
| 分子式: | C₆₃H₉₁CoN₁₃O₁₄P |
| SMILES: | NC(C[C@H]1[C@@]2([H])[C@]3(C)[N]4=C([C@@H](CCC(N)=O)[C@]3(C)CC(N)=O)C(C)=C([C@](CC(N)=O)(C)[C@@H]5CCC(N)=O)[N]6=C5C=C(C(C)(C)[C@@H]7CCC(N)=O)[N]8=C7C(C)=C([C@@]1(CCC(NC[C@@H](C)O9)=O)C)[N-]2[Co+3]486([CH3-])[N](C%10=CC(C)=C(C)C=C%11%10)=CN%11[C@@H](O[C@@H |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Methylcobalamin (CH3-B12) 是维生素B12的一种形式。 |
| IC50和靶点: | |
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Okada, K., Tanaka, H., Temporin, K., et al.Methylcobalamin increases Erk1/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury modelExp. Neurol.222(2),191-203(2010)
Xu, J., Wang, W., Zhong, X.X., et al.Methylcobalamin ameliorates neuropathic pain induced by vincristine in rats: Effect on loss of peripheral nerve fibers and imbalance of cytokines in the spinal dorsal hornMol. Pain12,1744806916657089(2016)
Ikeda, K., Iwasaki, Y., and Kaji, R.Neuroprotective effect of ultra-high dose methylcobalamin in wobbler mouse model of amyotrophic lateral sclerosisJ. Neurol. Sci.354(1-2),70-74(2015)
Liao, W.C., Chen, J.R., Wang, Y.J., et al.Methylcobalamin, but not methylprednisolone or pleiotrophin, accelerates the recovery of rat biceps after ulnar to musculocutaneous nerve transferNeuroscience141(3),934-949(2010)
