L-5-Hydroxytryptophan
Cat. No.：YN372938
CAS No. ：4350-09-8
| 产品名称: | L-5-Hydroxytryptophan |
| CAS No.: | 4350-09-8 |
| Chemical Name: | 5-hydroxy-L-tryptophan |
| Synonyms: | L-5-HTP; Oxitriptan |
| 分子量: | 220.22 |
| 分子式: | C₁₁H₁₂N₂O₃ |
| SMILES: | N[C@@H](CC1=CNC2=CC=C(O)C=C12)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | L-5-Hydroxytryptophan (L-5-HTP) 是一种天然氨基酸和膳食补充剂，可作为抗抑郁剂、食欲抑制剂和睡眠辅助剂，是神经递质血清素的前体，是利血平 (reserpine) 的拮抗剂。L-5-Hydroxytryptophan (L-5-HTP) 可用于纤维肌痛症、肌阵挛、偏头痛和小脑共济失调的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Martinez, A., Knappskog, P.M., and Haavik, J.A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosyntheisCurr. Med. Chem.8(9),1077-1091(2001)
Haberzettl, R., Fink, H., and Bert, B.The murine serotonin syndrome - evaluation of responses to 5-HT-enhancing drugs in NMRI miceBehav. Brain Res.277,204-210(2015)
Laporta, J., Moore, S.A.E., Weaver, S.R., et al.Increasing serotonin concentrations alter calcium and energy metabolism in dairy cowsJ. Endocrinol.226(1),43-55(2015)
Schmid, C.L., and Bohn, L.M.Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a β-arrestin2/Src/Akt signaling complex in vivoJ. Neurosci.30(40),13513-13524(2010)
Cahill, G.M., and Besharse, J.C.Circadian regulation of melatonin in the retina of Xenopus laevis: imitation by serotonin availabilityJ. Neurochem.54(2),716-719(1990)
Sridharan, G.V., Choi, K., Klemashevich, C., et al.Prediction and quantification of bioactive microbiota metabolites in the mouse gutNat. Commun.5,5492(2014)
