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3,4-Dicaffeoylquinic acid

Cat. No.:YN373028

  • CAS No. :14534-61-3

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    • 产品名称: 3,4-Dicaffeoylquinic acid
      CAS No.: 14534-61-3
      Chemical Name: (1S,3R,4R,5R)-3,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,5-dihydroxy-cyclohexanecarboxylic acid
      Synonyms:异绿原酸B; 3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B
      分子量:516.45
      分子式:C₂₅H₂₄O₁₂
      SMILES:O=C([C@@]1(O)C[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[C@H](OC(/C=C/C3=CC=C(O)C(O)=C3)=O)[C@H](O)C1)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 3,4-Dicaffeoylquinic acid 是天然分离的,具有抗氧化,DNA 保护,神经保护和肝保护特性。3,4-Dicaffeoylquinic acid 具有凋亡介导的细胞毒性和 α-葡萄糖苷酶 (α-glucosidase) 抑制作用。3,4-Dicaffeoylquinic acid 具有独特的抗病毒作用机制,即通过增加 TRAIL 来提高病毒清除率。
      IC50和靶点:
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    • Oh, H., Kang, D.-G., Lee, S., et al.Angiotensin converting enzyme inhibitors from Cuscuta japonica ChoisyJ. Ethnopharmacol.83(1-2),105-108(2012)

      Yoshimoto, M., Yahara, S., Okuno, S., et al.Antimutagenicity of mono-, di-, and tricaffeoylquinic acid derivatives isolated from sweetpotato (Ipomoea batatas L.) leafBiosci. Biotechnol. Biochem.66(11),2336-2341(2002)

      Ooi, K.L., Muhammad, T.S.T., Tan, M.L., et al.Cytotoxic, apoptotic and anti-α-glucosidase activities of 3,4-di-O-caffeoyl quinic acid, an antioxidant isolated from the polyphenolic-rich extract of Elephantopus mollis KunthJ. Ethnopharmacol.135(3),685-695(2011)

      Takemura, T., Urushisaki, T., Fukuoka, M., et al.3,4-Dicaffeoylquinic acid, a major constituent of Brazilian propolis, increases TRAIL expression and extends the lifetimes of mice infected with the influenza A virusEvid. Based Complement. Alternat. Med.2012:946867,(2012)

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