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4,5-Dicaffeoylquinic acid

Cat. No.:YN373029

  • CAS No. :57378-72-0

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    • 参考文献
    • 产品名称: 4,5-Dicaffeoylquinic acid
      CAS No.: 57378-72-0
      Chemical Name: (1R,3R,4S,5R)-3,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,5-dihydroxy-cyclohexanecarboxylic acid
      Synonyms:3,4-Dicaffeoylquinic acid; 4,5-Dicaffeoylquinic acid
      分子量:516.45
      分子式:C₂₅H₂₄O₁₂
      SMILES:O=C([C@]1(O)C[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[C@@H](OC(/C=C/C3=CC=C(O)C(O)=C3)=O)[C@H](O)C1)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 异绿原酸 C (4,5-Dicaffeoylquinic acid) 是一种天然化合物,具有保护肝脏、抗乙肝的潜能。
      IC50和靶点:
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    • Bogaevskii, A.K., Dranik, L.I., and Borisov, M.I.The hydroxycinnamic acids of Galium fagetorum and G. pseudomollugoChem. Nat. Compd.6(6),761-762(1970)

      Chen, Y.-L., Hwang, T.-L., Yu, H.-P., et al.Ilex kaushue and its bioactive component 3,5-dicaffeoylquinic acid protected mice from lipopolysaccharide-induced acute lung injurySci. Rep.6,34243(2016)

      Robinson, W.E., Jr., Cordeiro, M., Abdel-Malek, S., et al.Dicaffeoylquinic acid inhibitors of human immunodeficiency virus integrase: Inhibition of the core catalytic domain of human immunodeficiency virus integraseMol. Pharmacol.50(4),846-855(1996)

      dos Santos, M.D., Chen, G., Almeida, M.C., et al.Effects of caffeoylquinic acid derivatives and C-flavonoid from Lychnophora ericoides on in vitro inflammatory mediator productionNat. Prod. Commun.5(5),733-740(2010)

      Ha, J.H., and Park, S.N.Mechanism underlying inhibitory effect of six dicaffeoylquinic acid isomers on melanogenesis and the computational molecular modeling studiesBioorg. Med. Chem.26(14),4201-4208(2018)

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