Ecdysone
Cat. No.：YN373067
| 产品名称: | Ecdysone |
| CAS No.: | 3604-87-3 |
| Chemical Name: | (5β)-2β,3β,14,22R,25-pentahydroxy-cholest-7-en-6-one |
| Synonyms: | 蜕皮甾酮; α |
| 分子量: | 464.63 |
| 分子式: | C₂₇H₄₄O₆ |
| SMILES: | O[C@]([C@@]12C)(CC[C@]1([H])[C@H](C)[C@H](O)CCC(C)(O)C)C([C@@](CC2)([H])[C@]([C@@]3([H])C[C@H]4O)(C[C@@H]4O)C)=CC3=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ecdysone (α-Ecdysone) 是昆虫和草药中的主要类固醇激素，可以激活盐皮质激素受体 (MR) 并诱导细胞凋亡 (apoptosis)。Ecdysone 通过其活性代谢物 20-羟基蜕皮激素 (Crustecdysone; 20E; HY-N6979) 在协调发育过渡和体内稳态睡眠调节中起重要作用。 |
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Fallon, A.M., and Gerenday, A.Ecdysone and the cell cycle: Investigations in a mosquito cell lineJ. Insect Physiol.56(10),1396-1401(2010)
Carrow, G.M., Calabrese, R.L., and Williams, C.M.Spontaneous and evoked release of prothoracicotropin from multiple neurohemal organs of the tobacco hornwormProc. Natl. Acad. Sci. USA78(9),5866-5870(1981)
Cherbas, L., and Cherbas, P.Distribution and metabolism of α-ecdysone in pupae of the silkworm Antheraea polyphemusBiol. Bull.138(2),115-128(1970)
