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> 产品中心 > 抑制剂 & 激动剂 > Metabolic Enzyme/Protease > Endogenous Metabolite

Gypenoside XVII

Cat. No.:YN373131

  • CAS No. :80321-69-3

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    • 生物活性
    • 参考文献
    • 产品名称: Gypenoside XVII
      CAS No.: 80321-69-3
      Chemical Name: 3β-(β-D-glucopyranosyloxy)-12β-hydroxydammar-24-en-20-yl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside
      Synonyms:Gynosaponin S
      分子量:947.15
      分子式:C₄₈H₈₂O₁₈
      SMILES:C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O[C@]([C@@H]([C@@H](O)[C@@H]4O)O)([H])O[C@@H]4CO)C)(CC[C@@]2([H])C3(C)C)[C@]5([C@@]1([H])[C@]([C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@@H](O)[C@@H]6O)O)O[C@@H]6CO[C@@H]([C@@H]([C@@H](O)[C@@H]7O)O)O[C@@H]7CO)([H])CC5)
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Gypenoside XVII 是一种属于绞股蓝皂甙类的新型植物雌激素,可激活雌激素受体 (estrogen receptors)。
      IC50和靶点:
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    • Meng, X., Luo, Y., Liang, T., et al.Gypenoside XVII enhances lysosome biogenesis and autophagy flux and accelerates autophagic clearance of amyloid-β through TFEB activationJ. Alzheimers Dis.52(3),1135-1150(2016)

      Yang, K., Zhang, H., Luo, Y., et al.Gypenoside XVII prevents atherosclerosis by attenuating endothelial apoptosis and oxidative stress: Insight into the ERα-mediated PI3K/Akt pathwayInt. J. Mol. Sci.18(2),77(2017)

      Sun, T., Duan, L., Li, J., et al.Gypenoside XVII protects against spinal cord injury in mice by regulating the microRNA‑21‑mediated PTEN/AKT/mTOR pathwayInt. J. Mol. Med.48(2),146(2021)

      Luo, Y., Dong, X., Lu, S., et al.Gypenoside XVII alleviates early diabetic retinopathy by regulating Müller cell apoptosis and autophagy in db/db miceEur. J. Pharmacol.895,173893(2021)

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