alpha-Cyperone
Cat. No.:YN373165
CAS No. :473-08-5
产品名称: | alpha-Cyperone |
CAS No.: | 473-08-5 |
Chemical Name: | (4aS,7R)-4,4a,5,6,7,8-hexahydro-1,4a-dimethyl-7-(1-methylethenyl)-2(3H)-naphthalenone |
Synonyms: | α-Cyperone; (+)-α-Cyperone |
分子量: | 218.33 |
分子式: | C₁₅H₂₂O |
SMILES: | O=C1C(C)=C2C[C@H](C(C)=C)CC[C@@]2(C)CC1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | alpha-Cyperone (α-Cyperone) 与 Cox-2, IL-6, Nck-2, Cdc42, Rac1 的表达下调相关,从而能够降低炎症反应。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Jung, S.-H., Kim, S.J., Jun, B.-G., et al.α-Cyperone, isolated from the rhizomes of Cyperus rotundus, inhibits LPS-induced COX-2 expression and PGE2 production through the negative regulation of NFκB signalling in RAW 264.7 cellsJ. Ethnopharmacol.147(1),208-214(2013)
Huang, B., Liu, J., Fu, S., et al.α-Cyperone attenuates H2O2-induced oxidative stress and apoptosis in SH-SY5Y cells via activation of Nrf2Front. Pharmacol.11,281(2020)
Xu, H.-B., Ma, Y.-B., Huang, X.-Y., et al.Bioactivity-guided isolation of anti-hepatitis B virus active sesquiterpenoids from the traditional Chinese medicine: Rhizomes of Cyperus rotundusJ. Ethnaopharmacol.171,131-140(2015)