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alpha-Cyperone

Cat. No.:YN373165

  • CAS No. :473-08-5

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    • 产品名称: alpha-Cyperone
      CAS No.: 473-08-5
      Chemical Name: (4aS,7R)-4,4a,5,6,7,8-hexahydro-1,4a-dimethyl-7-(1-methylethenyl)-2(3H)-naphthalenone
      Synonyms:α-Cyperone; (+)-α-Cyperone
      分子量:218.33
      分子式:C₁₅H₂₂O
      SMILES:O=C1C(C)=C2C[C@H](C(C)=C)CC[C@@]2(C)CC1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: alpha-Cyperone (α-Cyperone) 与 Cox-2, IL-6, Nck-2, Cdc42, Rac1 的表达下调相关,从而能够降低炎症反应。
      IC50和靶点:
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    • Jung, S.-H., Kim, S.J., Jun, B.-G., et al.α-Cyperone, isolated from the rhizomes of Cyperus rotundus, inhibits LPS-induced COX-2 expression and PGE2 production through the negative regulation of NFκB signalling in RAW 264.7 cellsJ. Ethnopharmacol.147(1),208-214(2013)

      Huang, B., Liu, J., Fu, S., et al.α-Cyperone attenuates H2O2-induced oxidative stress and apoptosis in SH-SY5Y cells via activation of Nrf2Front. Pharmacol.11,281(2020)

      Xu, H.-B., Ma, Y.-B., Huang, X.-Y., et al.Bioactivity-guided isolation of anti-hepatitis B virus active sesquiterpenoids from the traditional Chinese medicine: Rhizomes of Cyperus rotundusJ. Ethnaopharmacol.171,131-140(2015)

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