Palmitic acid
Cat. No.:YN373179
产品名称: | Palmitic acid |
CAS No.: | 57-10-3 |
Chemical Name: | hexadecanoic acid |
Synonyms: | hexadecanoic acid, Cetylic acid |
分子量: | 256.42 |
分子式: | C₁₆H₃₂O₂ |
SMILES: | CCCCCCCCCCCCCCCC(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Palmitic acid 是一种常见于动物和植物中的长链饱和脂肪酸。Palmitic acid 可以诱导小鼠颗粒细胞中葡萄糖调节蛋白 78 (GRP78) 和 CCAAT/增强子结合蛋白同源蛋白 (CHOP) 的表达。 |
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Fatima, S., Hu, X., Gong, R.-H., et al.Palmitic acid is an intracellular signaling molecule involved in disease developmentCell. Mol. Life Sci.76(13),2547-2557(2019)
Santos, M.J., López-Jurado, M., Llopis, J., et al.Influence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patientsAnn. Nutr. Metab.39(1),52-62(1995)
Binker-Cosen, M.J., Richards, D., Oliver, B., et al.Palmitic acid increases invasiveness of pancreatic cancer cells AsPC-1 through TLR4/ROS/NF-κB/MMP-9 signaling pathwayBiochem. Biophys. Res. Commun.484(1),152-158(2017)
Lee, J.Y., Sohn, K.H., Rhee, S.H., et al.Saturated fatty acids, but not unsaturated fatty acids, induced the expression of cyclooxygenase-2 mediated through Toll-like receptor 4J. Biol. Chem.276(20),16683-16689(2001)
Karasawa, T., Kawashima, A., Usui-Kawanishi, F., et al.Saturated fatty acids undergo intracellular crystallization and activate the NLRP3 inflammasome in macrophagesArterioscler. Thromb. Vasc. Biol.38(4),744-756(2018)
Marwarha, G., Rostad, S., Lilek, J., et al.Palmitate increases β-site AβPP-cleavage enzyme 1 activity and amyloid-β genesis by evoking endoplasmic reticulum stress and subsequent C/EBP homologous protein activationJ. Alzheimers Dis.57(3),907-925(2017)
Knowles, C.J., Cebova, M., and Pinz, I.M.Palmitate diet-induced loss of cardiac caveolin-3: A novel mechanism for lipid-induced contractile dysfunctionPLoS One8(4),e61369(2013)
Yi, L.-Z., He, J., Liang, Y.-Z., et al.Plasma fatty acid metabolic profiling and biomarkers of type 2 diabetes mellitus based on GC/MS and PLS-LDAFEBS Lett.580(30),6837-6845(2006)
Kabagambe, E.K., Tsai, M.Y., Hopkins, P.N., et al.Erythrocyte fatty acid composition and the metabolic syndrome: A National Heart, Lung, and Blood Institute GOLDN studyClin. Chem.54(1),154-162(2008)