Ganoderic acid A
Cat. No.：YN373207
| 产品名称: | Ganoderic acid A |
| CAS No.: | 81907-62-2 |
| Chemical Name: | (25R)-7β,15α-dihydroxy-3,11,23-trioxo-lanost-8-en-26-oic acid |
| Synonyms: | 灵芝酸 A,灵芝酸A |
| 分子量: | 516.67 |
| 分子式: | C₃₀H₄₄O₇ |
| SMILES: | CC1(C)C(CC[C@]2(C)C3=C([C@@]4([C@@H](O)C[C@@H]([C@]4(CC3=O)C)[C@H](C)CC(C[C@@H](C)C(O)=O)=O)C)[C@@H](O)C[C@@]12[H])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ganoderic acid A 能够抑制JAK-STAT3信号通路，也能抑制细胞增殖，存活率和 ROS。 |
| IC50和靶点: | |
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Gill, B.S., Kumar, S., and Gill, N.Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancerMol. Biol. Rep.43(12),1411-1422(2016)
Chi, B., Wang, S., Bi, S., et al.Effects of ganoderic acid A on lipopolysaccharide-induced proinflammatory cytokine release from primary mouse microglia culturesExp. Ther. Med.15(1),847-853(2018)
Wan, B., Li, Y., Sun, S., et al.Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in miceBiosci. Rep.39(5),BSR20190301(2019)
Zhu, J., Jin, J., Ding, J., et al.Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathwayChem. Biol. Interact.290,77-87(2018)
