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Ergothioneine

Cat. No.:YN373228

  • CAS No. :497-30-3

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Ergothioneine
      CAS No.: 497-30-3
      Chemical Name: (αS)-α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium, inner salt
      Synonyms:麦角硫因; L-(+)
      分子量:229.30
      分子式:C₉H₁₅N₃O₂S
      SMILES:S=C1NC(C[C@@H](C([O-])=O)[N+](C)(C)C)=CN1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Ergothioneine 是组氨酸甜菜碱的咪唑-2-硫酮衍生物,是由某些细菌和真菌合成的。Ergothioneine 通常被认为是抗氧化剂。
      IC50和靶点:
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      In Vivo:
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    • Askari, A., and Melville, D.B.The reaction sequence in ergothioneine biosynthesis: Hercynine as an intermediateJ. Biol. Chem.237,1615-1618(1962)

      Rahman, I.Pharmacological antioxidant strategies as therapeutic interventions for COPDBiochim. Biophys. Acta1822(5),714-728(2012)

      Misiti, F., Castagnola, M., Zuppi, C., et al.Role of ergothioneine on S-nitrosoglutathione catabolismBiochem. J.356(3),799-804(2001)

      Cheah, I.K., and Halliwell, B.Ergothioneine; antioxidant potential, physiological function and role in diseaseBiochim. Biophys. Acta1822,784-793(2012)

      Aruoma, O.I., Spencer, J.P.E., and Mahmood, N.Protection against oxidative damage and cell death by the natural antioxidant ergothioneineFood Chem. Toxicol.37(11),1043-1053(1999)

      Nakamura, T., Yoshida, K., Yabuuchi, H., et al.Functional characterization of ergothioneine transport by rat organic cation/carnitine transporter Octn1 (slc22a4)Biol. Pharm. Bull.31(8),1580-1584(2008)

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