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Taurochenodeoxycholic acid

Cat. No.:YN373241

  • CAS No. :516-35-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Taurochenodeoxycholic acid
      CAS No.: 516-35-8
      Chemical Name: 2-[[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid
      Synonyms:牛磺鹅去氧胆酸; 12-Deoxycholyltaurine
      分子量:499.70
      分子式:C₂₆H₄₅NO₆S
      SMILES:C[C@@]1([C@@]2([H])[C@H](C)CCC(NCCS(=O)(O)=O)=O)[C@](CC2)([H])[C@@]([C@@H](C[C@]3([H])C[C@H](O)CC4)O)([H])[C@]([C@]34C)([H])CC1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Taurochenodeoxycholic acid (12-Deoxycholyltaurine) 是动物胆汁酸的主要生物活性物质之一。Taurochenodeoxycholic acid 可诱导细胞凋亡 (apoptosis),并具有明显的抗炎和免疫调节作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
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      Solvent & Solubility:
    • Hoffman, A.F.The continuing importance of bile acids in liver and intestinal diseaseArch. Intern. Med.159(22),2647-2658(1999)

      Schmid, A., Neumann, H., Karrasch, T., et al.Bile acid metabolome after an oral lipid tolerance test by liquid chromatography-tandem mass spectrometry (LC-MS/MS)PLoS One11(2),e0148869(2016)

      Wang, X., Xie, G., Zhao, A., et al.Serum bile acids are associated with pathological progression of hepatitis B-induced cirrhosisJ. Proteome Res.15(4),1126-1134(2016)

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