2,5-Dihydroxybenzoic acid
Cat. No.：YN374013
| 产品名称: | 2,5-Dihydroxybenzoic acid |
| CAS No.: | 490-79-9 |
| Chemical Name: | 2,5-dihydroxy-benzoic acid |
| Synonyms: | DHB; 2,5-dihydroxybenzoic acid; 5-Hydroxysalicylic acid; Gentianic acid; Carboxyhydroquinone; Hydroquinonecarboxylic acid |
| 分子量: | 154.12 |
| 分子式: | C₇H₆O₄ |
| SMILES: | OC(C=C1)=C(C(O)=O)C=C1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2,5-Dihydroxybenzoic acid 是苯甲酸的代谢物，也是纤维母细胞生长因子(fibroblast growth factor)的强效抑制剂。 |
| IC50和靶点: | |
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Joshi, R.P., Gangabhagirathi, R., Venu, S., et al.Antioxidant activity and free radical scavenging reactions of gentisic acid: In-vitro and pulse radiolysis studiesFree Radic. Res.46(1),11-20(2012)
Ashidate, K., Kawamura, M., Mimura, D., et al.Gentisic acid, an aspirin metabolite, inhibits oxidation of low-density lipoprotein and the formation of cholesterol ester hydroperoxides in human plasmaEur. J. Pharmacol.513(3),173-179(2005)
Cunha, J.F., Campestrini, F.D., Calixto, J.B., et al.The mechanism of gentisic acid-induced relaxation of the guinea pig isolated trachea: The role of potassium channels and vasoactive intestinal peptide receptorsBraz. J. Med. Biol. Res.34(4),381-388(2001)
Sun, S., Kee, H.J., Ryu, Y.L., et al.Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failureSci. Rep.9(1),3018(2019)
Mink, S., Roy Chowdhury, S.K., Gotes, J., et al.Gentisic acid sodium salt, a phenolic compound, is superior to norepinephrine in reversing cardiovascular collapse, hepatic mitochondrial dysfunction and lactic acidemia in Pseudomonas aeruginosa septic shock in dogsIntensive Care Med. Exp.4(1),24(2016)
