Cyclic N-Acetyl-D-mannosamine
Cat. No.:YN374346
| 产品名称: | Cyclic N-Acetyl-D-mannosamine |
| CAS No.: | 7772-94-3 |
| Chemical Name: | 2-(acetylamino)-2-deoxy-β-D-mannopyranose |
| Synonyms: | Cyclic ManNAc |
| 分子量: | 221.21 |
| 分子式: | C₈H₁₅NO₆ |
| SMILES: | CC(N[C@@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O)CO)O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cyclic N-Acetyl-D-mannosamine (Cyclic ManNAc) 是一种内源性代谢产物。 |
| IC50和靶点: | |
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Schwarzkopf, M., Knobeloch, K.P., Rohde, E., et al.Sialylation is essential for early development in miceProc. Natl. Acad. Sci. USA99(8),5267-5270(2002)
Galeano, B., Klootwijk, R., Manoli, I., et al.Mutation in the key enzyme of sialic acid biosynthesis causes severe glomerular proteinuria and is rescued by N-acetylmannosamineJ. Clin. Invest.117(6),1585-1594(2007)
Gagiannis, D., Gossrau, R., Reutter, W., et al.Engineering the sialic acid in organs of mice using N-propanoylmannosamineBiochim. Biophys. Acta1770,297-306(2007)