Vidupiprant
Cat. No.：YN322170
CAS No. ：1169483-24-2
| 产品名称: | Vidupiprant |
| CAS No.: | 1169483-24-2 |
| Chemical Name: | 5-Chloro-4-[2-[[(2-chloro-4-cyclopropylphenyl)sulfonyl]amino]-4-[[(1,1-dimethylethyl)amino]carbonyl]phenoxy]-2-fluorobenzeneacetic Acid; Vidupiprant; 2-(4-(4-(tert-Butylcarbamoyl)-2-(2-chloro-4-cyclopropylphenylsulfonamido)phenoxy)-5-chloro-2-fluorophenyl |
| Synonyms: | AMG 853 |
| 分子量: | 609.49 |
| 分子式: | C28H27Cl2FN2O6S |
| SMILES: | CC(C1=C2C(C=CC=C2)=CC=C1N/3C)(C)C3=C/C=C/C4=[N+](CCCCCC(ON(C(CC5)=O)C5=O)=O)C6=CC=C7C(C=CC=C7)=C6C4(C)C.FB(F)F.[F-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Vidupiprant (AMG 853) 是一种苯乙酸衍生物，也是一种有效的口服活性的CRTH2 (DP2)和prostanoid D receptor (DP or DP1)双重拮抗剂，在缓冲液中的IC50分别为 3 nM 和 4 nM，在人血浆中的IC50分别为 8 nM 和 35 nM。Vidupiprant 可用于哮喘的研究。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Busse, W.W. et al.: J. Allergy Clin. Immunol., 131, 339 (2013)
