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Hemin

Cat. No.:YN270383

  • CAS No. :16009-13-5

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    • 参考文献
    • 产品名称: Hemin
      CAS No.: 16009-13-5
      Chemical Name: (SP-5-13)-chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,8-dipropanoato(4-)-κN21, κN22, κN23, κN24]-ferrate(2-), dihydrogen
      Synonyms:氯化血红素;
      分子量:651.94
      分子式:C₃₄H₃₂ClFeN₄O₄
      SMILES:[Cl-][Fe+3]123[N-]4C5=C(CCC([O-])=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC([O-])=O)=[N]3C8=C5.[H+].[H+]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Hemin 是含铁的卟啉化合物。Hemin 是血红素加氧酶(HO)-1诱导剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Taraha, S.M., Traugh, J.A., Sharp, S.B., et al.Effect of hemin on site-specific phosphorylation of eukaryotic initiation factor 2Proc. Natl. Acad. Sci. USA75(2),789-793(1978)

      Vesely, M.J.J., Exon, D.J., Clark, J.E., et al.Heme oxygenase-1 induction in skeletal muscle cells: hemin and sodium nitroprusside are regulators in vitroAm. J. Physiol.275(4 Pt 1),C1087-1094(1998)

      Lindenblatt, N., Bordel, R., Schareck, W., et al.Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivoArterioscler. Thromb. Vasc. Biol.24(3),601-606(2004)

      Botros, F.T., Prieto-Carrasquero, M.C., Martin, V.L., et al.Heme oxygenase induction attenuates afferent arteriolar autoregulatory responsesAm. J. Physiol. Renal Physiol.295(4),F904-F911(2008)

      Labbé, R.F., Finch, C.A., Smith, N.J., et al.Erythrocyte protoporphyrin/heme ratio in the assessment of iron statusClin. Chem.25(1),87-92(1979)

      Bissell, D.M., and Wang, B.Acute hepatic porphyriaJ. Clin. Transl. Hepatol.3(1),17-26(2015)

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