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Lutein

Cat. No.:YN270653

  • CAS No. :127-40-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Lutein
      CAS No.: 127-40-2
      Chemical Name: (6'R)-β,ε-carotene-3R,3'R-diol
      Synonyms:Xanthophyll
      分子量:568.9
      分子式:C40H56O2
      SMILES:O[C@@H]1CC(C)(C)[C@@H](/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(/C=C/C=C(/C=C/C2=C(C)C[C@@H](O)CC2(C)C)C)C)C(C)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Lutein (Xanthophyll) 是一种类胡萝卜素,具有抗炎作用。Lutein 具有多种有益作用,尤其是对眼睛健康。Lutein 通过影响活性氧 (ROS) 发挥抗炎、抗氧化酶、抗凋亡 (apoptosis) 等生物活性。Lutein 能够到达大脑,显示出抗抑郁类和神经保护作用。Lutein 具有口服活性。
      IC50和靶点:
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    • Nanjaiah, H., and Vallikannan, B.Lutein upregulates the PGC-1α, NRF1, and TFAM expression by AMPK activation and downregulates ROS to maintain mtDNA integrity and mitochondrial biogenesis in hyperglycemic ARPE-19 cells and rat retinaBiotechnol. Appl. Biochem.66(6),999-1009(2019)

      Hajizadeh-Sharafabad, F., Ghoreishi, Z., Maleki, V., et al.Mechanistic insights into the effect of lutein on atherosclerosis, vascular dysfunction, and related risk factors: A systematic review of in vivo, ex vivo and in vitro studiesPharmacol. Res.149,104477(2019)

      Ouyang, B., Li, Z., Ji, X., et al.The protective role of lutein on isoproterenol-induced cardiac failure rat model through improving cardiac morphology, antioxidant status via positively regulating Nrf2/HO-1 signalling pathwayPharm. Biol.57(1),529-535(2019)

      Bungau, S., Abdel-Daim, M., Tit, D.M., et al.Health benefits of polyphenols and carotenoids in age-related eye diseasesOxid. Med. Cell. Longev.,9783429(2019)

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