MPT0E028
Cat. No.：YN270657
CAS No. ：1338320-94-7
| 产品名称: | MPT0E028 |
| CAS No.: | 1338320-94-7 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 344.385 |
| 分子式: | C17H16N2O4S |
| SMILES: | C(NO)(=O)/C=C/C1C=CC2=C(C=1)CCN2S(C1=CC=CC=C1)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MPT0E028 是一种口服有效的，选择性HDAC抑制剂，对HDAC1，HDAC2 和HDAC6的IC50分别为 53.0 nM，106.2 nM，29.5 nM。MPT0E028 通过诱导细胞凋亡降低 B 细胞淋巴瘤的活力，同时具有有效的直接Akt靶向能力，降低 B 细胞淋巴瘤中的Akt磷酸化。MPT0E028 具有良好的抗癌能力。 |
| IC50和靶点: | [{name:"HDAC1:53.0 nM (IC50)"},{name: "HDAC2:106.2 nM (IC50)"},{name: "HDAC6:29.5 nM (IC50)"},{name: "HDAC8:2532.6 nM (IC50)"}] |
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