Taurohyodeoxycholic acid sodium
Cat. No.：YN270747
CAS No. ：38411-85-7
| 产品名称: | Taurohyodeoxycholic acid sodium |
| CAS No.: | 38411-85-7 |
| Chemical Name: | 2-[[(3α,5β,6α)-3,6-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt |
| Synonyms: | 牛磺去氧胆酸钠 |
| 分子量: | 521.68647 |
| 分子式: | C26H44NO6S • Na |
| SMILES: | C[C@H](CCC(NCCS([O-])(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])C[C@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na+] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Taurohyodeoxycholic acid (THDCA) sodium 是二级胆汁酸羟基去氧胆酸的牛磺酸共轭形式。Taurohyodeoxycholic acid 还能降低 TNBS 诱导的溃疡性结肠炎小鼠模型中髓过氧化物酶、TNF-α 和IL-6的活性和表达，以及抑制结肠损伤。 |
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Angelico, M., Mogavero, L., Baiocchi, L., et al.Dissolution of human cholesterol gallstones in bile salt/lecithin mixtures: effect of bile salt hydrophobicity and various pHsScand. J. Gastroenterol.30(12),1178-1185(1995)
Angelico, M., Baiocchi, L., Nistri, A., et al.Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the ratDig. Dis. Sci.39(11),2389-2397(1994)
Roda, A., Piazza, F., Baraldini, M., et al.Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the ratHepatology27(2),520-525(1998)
He, J., Liang, J., Zhu, S., et al.Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in miceEur. J. Pharmacol.670(1),229-235(2011)
