YUM70
Cat. No.：YN270753
CAS No. ：423145-35-1
规格
价格(RMB)
库存
| 产品名称: | YUM70 |
| CAS No.: | 423145-35-1 |
| Chemical Name: | |
| Synonyms: | MLS000548411;SMR000172091;N-[Benzo[1,3]dioxol-5-yl-(5-chloro-8-hydroxy-quinolin-7-yl)-methyl]-butyramide;BAS 02169251;Oprea1_596028;Oprea1_626646;BDBM77529;cid_3138755;HMS2575N03;DNDI1417995;N-[1,3-benzodioxol-5-yl-(5-chloro-8-hydroxyquinolin-7-yl)methyl] |
| 分子量: | 398.8396 |
| 分子式: | C21H19ClN2O4 |
| SMILES: | ClC1=C2C([H])=C([H])C([H])=NC2=C(C(=C1[H])C([H])(C1C([H])=C([H])C2=C(C=1[H])OC([H])([H])O2)N([H])C(C([H])([H])C([H])([H])C([H])([H])[H])=O)O[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | YUM70 是一种有效和选择性的葡萄糖调节蛋白 78 (GRP78) 抑制剂，抑制全长蛋白的 GRP78 ATPase 活性的IC50值为 1.5 μM。YUM70 可诱导内质网 (ER) 应激介导的胰腺癌细胞凋亡。YUM70 在胰腺癌异种移植模型中也具有体内功效。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
