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Belnacasan

Cat. No.：273404-37-8

  • CAS No. ：273404-37-8

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    • 产品名称: Belnacasan
      CAS No.: 273404-37-8
      Chemical Name:
      Synonyms:VX-765
      分子量:509.00
      分子式:C₂₄H₃₃ClN₄O₆
      SMILES:ClC1=C(N)C=CC(C(N[C@@H](C(C)(C)C)C(N2[C@H](C(N[C@H]3CC(O[C@H]3OCC)=O)=O)CCC2)=O)=O)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Wannamaker, W., Davies, R., Namchuk, M., et al.(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1β and IL-18J. Pharmacol. Exp. Ther.321(2),509-516(2007)', 'Maroso, M., Balosso, S., Rivizza, T., et al.Interleukin-1β biosynthesis inhibition reduces acute seizures and drug resistant chronic epileptic activity in miceNeurotherapeutics8(2),304-315(2011)
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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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