Rucaparib

Cat. No.：283173-50-2

CAS No. ：283173-50-2

产品名称:	Rucaparib
CAS No.:	283173-50-2
Chemical Name:
Synonyms:	瑞卡帕布; AG014699; PF-01367338
分子量:	323.36
分子式:	C₁₉H₁₈FN₃O
SMILES:	FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Yuan, Y., Liao, Y.M., Hsueh, C.T., et al.Novel targeted therapeutics: Inhibitors of MDM2, ALK and PARPJ. Hematol. Oncol.4(16),1-14(2011)', 'Javle, M., and Curtin, N.J.The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapyTher. Adv. Med. Oncol.3(6),257-267(2011)', 'Plummer, R.Poly(ADP-ribose) polymerase inhibition: A new direction for BRCA and triple-negative breast cancer?Breast Cancer Res.13(4),1-6(2011)', 'Johnson, N., Li, Y.C., Walton, Z.E., et al.Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibitionNat. Med.17(7),875-882(2011)', 'Rowe, B.P., and Glazer, P.M.Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanismsBreast Cancer Res.12(2),1-11(2010)', 'Daniel, R.A., Rozanska, A.L., Mulligan, E.A., et al.Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly(ADP-ribose) polymerase inhibitor AG-014699Br. J. Cancer103(10),1588-1596(2010)', 'Drew, Y., Mulligan, E.A., Vong, W.T., et al.Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2JNCI103(4),334-346(2011)