COH34
Cat. No.：YN480952
CAS No. ：906439-72-3
规格
价格(RMB)
库存
| 产品名称: | COH34 |
| CAS No.: | 906439-72-3 |
| Chemical Name: | |
| Synonyms: | 1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol |
| 分子量: | 293.38 |
| 分子式: | C₁₈H₁₅NOS |
| SMILES: | CC1=CC=C(S/N=C/C2=C3C=CC=CC3=CC=C2O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | COH34 是一种有效且特异性的聚 (ADP-核糖) 糖水解酶(PARG)抑制剂，IC50为 0.37 nM。COH34 与 PARG 的催化结构域 (Kd= 0.547 μM) 结合，从而延长了 DNA 损伤处的 PARylation 并捕获了 DNA 修复因子。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
