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SSR240612

Cat. No.：464930-42-5

  • CAS No. ：464930-42-5

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    • 产品名称: SSR240612
      CAS No.: 464930-42-5
      Chemical Name:
      Synonyms:SSR-240612; SSR240612; SSR 240612
      分子量:793.41
      分子式:C₄₂H₅₃ClN₄O₇S
      SMILES:O=S(N[C@@H](C1=CC=C2C(OCO2)=C1)CC(N[C@@H](C(N(C)C(C)C)=O)CC3=CC=C(CN([C@@H]4C)[C@H](CCC4)C)C=C3)=O)(C5=CC(C=CC(OC)=C6)=C6C=C5)=O.Cl[H]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Gougat, J., Ferrari, B., Sarran, L., et al.SSR240612 [(2R)-2-[((3R)-3-(1,3-benzodioxol-5-yl)-3-[[(6-methoxy-2-naphthyl)sulfonyl]amino]propanoyl)amino]-3-(4-[[2R,6S)-2,6-dimethylpiperidinyl]methyl]phenyl)-N-isopropyl-N-methylpropanamide hydrochloride], a new nonpeptide antagonist of the bradykinin B1 receptor: Biochemical and pharmacological characterizationJ. Pharmacol. Exp. Ther.309(2),661-669(2004)', 'Huart, A., Klein, J., Gonzalez, J., et al.Kinin B1 receptor antagonism is equally efficient as angiotensin receptor 1 antagonism in reducing renal fibrosis in experimental obstructive nephropathy, but is not additiveFront. Pharmacol.6:8,(2015)', 'De Brito Gariepy, H., Carayon, P., Ferrari, B., et al.Contribution of the central dopaminergic system in the anti-hypertensive effect of kinin B1 receptor antagonists in two rat models of hypertensionNeuropeptides44(2),191-198(2010)', 'Dias, J.P., and Couture, R.Blockade of kinin B1 receptor reverses plasma fatty acids composition changes and body and tissue fat gain in a rat model of insulin resistanceDiabetes Obes. Metab.14(3),244-253(2012)
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