GR148672X
Cat. No.:YN480444
| 产品名称: | GR148672X |
| CAS No.: | 263890-70-6 |
| Chemical Name: | 4,4,4-trifluoro-1-(2-thienyl)-1,2,3-butanetrione, 2-[(3-methylphenyl)hydrazone] |
| Synonyms: | 4,4,4-三氟-1-(2-噻吩基)-1,2,3-丁三酮 2-[(3-甲基苯基)腙] |
| 分子量: | 340.32 |
| 分子式: | C₁₅H₁₁F₃N₂O₂S |
| SMILES: | O=C(C1=CC=CS1)/C(C(C(F)(F)F)=O)=N\NC2=CC=CC(C)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GR148672X 是一种三酰甘油水解酶 (TGH) 抑制剂,其IC50值为 4 nM,来自专利 WO 2001016358 A2。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Borg-Capra, C.S., Lehner, R.J., and Vance, D.E.Method of screening for triacyglycerol hydrolase inhibitorsWO 01/16358 A2,(2001)
Wei, E., Ben Ali, Y., Lyon, J., et al.Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditureCell Metab.11(3),183-193(2010)